The No. 2 Penn State Nittany Lions are 16-1 straight up and 14-1-2 against the spread over their last 17 games. The Nittany Lions will try to retain control of their destiny in the Big Ten with a road win this Saturday against the No. 6 Ohio State Buckeyes.

Penn State is a 6.5-point road underdog in Columbus at sportsbooks monitored by As a 17.5-point home underdog last season, the Nittany Lions upset the Buckeyes 24-21.

Penn State Nittany Lions at Ohio State Buckeyes

When: Saturday, October 28, 3:30 p.m. ET

Where: Ohio Stadium, Columbus, Ohio

Betting Line / Total: Ohio State -6.5 / 55 Points

Nittany Lions at Buckeyes OddsShark Matchup Report

Penn State Nittany Lions

Saquon Barkley added to his Heisman resume with last Saturday’s performance against Michigan, rushing for 108 yards and two touchdowns and catching three passes for 53 yards and a touchdown against one of the nation’s top defenses. Penn State had no trouble at all in dismantling the Wolverines 42-13.

Through a 7-0 SU and 5-1-1 ATS run through the 2017 schedule so far, Penn State has won its games by an average margin of victory of 23.1 points per game.

This will be Penn State’s first game as an underdog this season. The Nittany Lions are 3-1 SU and 4-0 ATS in their last four games as a dog per the OddsShark College Football Database.

Ohio State Buckeyes

Since suffering a stunning 31-16 loss to Oklahoma back in Week 2, the Buckeyes have been nothing short of dominant. Ohio State has mowed through its last five games with a 5-0 SU and 3-2 ATS record, averaging 53.2 points per game while allowing only 11.2 points per game.

With that said, each of the last four teams the Buckeyes have faced have losing records. This week’s test against an elite team will show the nation just how good this year’s Ohio State team really is.

Saturday’s total is set at 55 points. The OVER is 5-0 in Ohio State’s last five games against Big Ten opponents.

With Michigan now out of the picture with a 2-2 conference record, Penn State, Ohio State and Michigan State will battle for the top spot in the Big Ten East down the stretch. The winner of this game will emerge as the clear favorite to win the division and will control its destiny for a playoff spot.